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Plopper CG, Heidsiek JG, Weir AJ, St

In rats, TMAO increases with age and causes oxidative stress and inflammation in blood vessels, leading to endothelial (blood vessel lining) dysfunction, which increases the risk of heart disease [12]

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In addition to the direct assessment of microbial metabolites discussed above, the genomic content of microbes can be analyzed and used to predict their metabolic capabilities of the gut microbiota in health and disease, as well as for specific bacterial strains