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We calculated the ROR of the PTs ( n = 92) with no less than 5 reports of psychiatric AEs among treatments with GLP-1 RAs, using the entire FAERS database as a benchmark, and then performed a disproportionality analysis ( Supplementary Figure S1 )

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GLP-1RAs might have a direct impact on keratinocytes, as evidenced by the detection of GLP-1R and glucagon in neonatal mouse skin and cultured skin cells [203]

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doi: 10.1182/blood-2010-04-279893 246 ChirasaniSRLeukelPGottfriedEHochreinJStadlerKNeumannBet al

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The design of analogues with higher selectivity and effectiveness against Y2 receptors can maximize the therapeutic effect and minimize side effects

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