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MR is based on three key assumptions: 1) the genetic variants used as instruments for the exposure must be valid and robustly associated with the exposure, 2) there should be no measured or unmeasured confounding of the association between the genetic instrument and the outcome, and 3) the variants should have no independent effect on the outcome other than through the exposure of interest 17

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Unfortunately, these potent sprays are highly toxic to beneficial pollinators like bees and butterflies

When Carrey was cast in Ron Howard's 2000 adaptation, it couldn't have been a more perfect match