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Comparison to Other Bariatric Modalities Studies have shown that Roux-en-Y gastric bypass (RYGB) produces more sustained hormonal effects and greater remission of type 2 diabetes than LSG [35, 36]

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Importantly, Zepbound carries a boxed warning for risk of thyroid C-cell tumors and is contraindicated in patients with a personal or family history of medullary thyroid carcinoma (MTC) or in patients with Multiple Endocrine Neoplasia syndrome type 2 (MEN2)

Obesity is a chronic disease that often requires long-term treatment to achieve and maintain meaningful health outcomes