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Finally, it is not clear whether theobromine will exhibit a preferable anti-tussive profile compared to theophylline which is already approved for use in respiratory disease

Co-treatment with sodium arsenite and lipopolysaccharides (LPS) in L-02 hepatocarcinoma cell line induced NLRP3 inflammasome activation, leading to reduction in Akt and glycogen-synthase kinase 3 (GSK3) phosphorylation, and increased glycogen synthase phosphorylation levels (111)

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