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Some of these chemical messengers are free radicals, which are highly reactive species that can either gain or loose electrons, or in proper terminology, take part in oxidation or reduction reactions
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Furthermore, numerous studies have found that Januvia and Janumet can increase the rate of tumors and that patients who use incretin drugs (including Januvia and Janumet) can suffer from higher rates of pancreatic cancer and pancreatitis(however, this study was a small sample size and far from conclusive)
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