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In order to investigate the functional targeting of -cells by the aGLP1-E2 conjugate, we used Min6 insulin-secreting cells transfected with a luciferase reporter construct containing an estrogen response element (ERE-Luc) 7

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It activates the same fat-cell receptor pathway (beta-3 adrenergic) as AOD 9604, triggering stored fat to be released and burned

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