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Because GIP receptor activation affects fat metabolism through pathways separate from appetite control, there is a theoretical basis for better weight maintenance at lower tirzepatide doses compared to equivalent semaglutide doses

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One of the authors, Dr Andrew Hill of Liverpool Universitys pharmacology department, said: These low prices open the door to worldwide access to an essential medicine. The researchers also found that core patents on semaglutide were due to expire in 10 countries this year, including Brazil, China, India, South Africa, Turkey, Mexico and Canada from 21 March, opening the way to generic competition

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