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Besides, the d9-BB in the O15 hGM group increased in the beginning but dropped subsequently, whereas d9-BB in other three hGM groups increased continuously which suggested that the d9-BB may be consumed by the gut microbial community of O15 hGM group (Fig

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Clinically, FRDA is a progressive disease characterized by ataxia, areflexia, speech disturbance (dysarthria), sensory loss, motor dysfunction, cardiomyopathy, diabetes, and scoliosis (77)

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