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This suggests that these polysaccharides may exert antidepressant effects by modulating relevant trophic factors and neurotransmitters in depressed rats ( Ganoderma lucidum polysaccharides (GLP) were observed to elevate BDNF expression in the hippocampus of mice subjected to chronic social frustration stress ( The bioactive polysaccharide degraded porphyrin (DPR), extracted from Porphyra haitanensis , was utilized by Yi et al

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Also, the main markers of mitochondrial biogenesis (Ppargc1a, Nrf1, Tfam, Cytc), fusion (Mfn2), and mitophagy (Pink1 and Tfeb) were disturbed

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