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2 Materials and methods 2.1 Animals Sixty young male western Albino rats, approximately 3 weeks old, weighing about 6080 g, were obtained from the Experimental Surgery and Animal Laboratory at King Saud University (Riyadh, Saudi Arabia)

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Accordingly, both APR and GCL in the primary metabolic pathway are activated upon oxidation whereas the activity of enzymes that are part of the secondary pathway, APK and SAL1, is attenuated