Cysteine is the most limiting building block: those who eat little protein, or follow a diet poor in cysteine sources such as eggs, meat and legumes, give the body less raw material to work with
Similarly, increases in intima-media thickness of the common carotid arteries, presence of coronary heart disease, and the presence of peripheral artery disease correlated with the Pro/Leu genotype compared to those homozygous for the Pro allele in a study of type 2 diabetic patients in Japan [91], consistent with a role for this polymorphism in cardiovascular risk
Count data for the SARP cohort was obtained from Stephanie Christianson (UCSF) and as published recently (47)
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One thing we keep an eye on with frequent treatments is zinc levels , since high-dose glutathione might lower them over time