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AML is a hematological malignancy arising from hematopoietic stem progenitor cells, characterized by abnormal proliferation of primitive myeloid cells in bone marrow and peripheral blood ( Despite AKR1C3 not being overexpressed in leukemia compared to non-leukemic or healthy tissues, an increase in AKR1C3 expression has been observed in T-cell acute lymphoblastic leukemia (T-ALL) compared with other leukemia subtypes, including AML and B-cell acute lymphoblastic leukemia (B-ALL) (Wu et al., 2023)

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This guide breaks down what GLP-1 peptides are, how they are studied, and what makes each compound unique from a research perspective

doi: 10.1016/j.neubiorev.2017.09.029, 41 ImpeyD.de la SalleS.BaddeleyA.KnottV

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