Attenuated Gastric Ulcers, Seizures, Brain Lesions, Hepatomegaly, Fatty Liver, Breakdown of Liver Glycogen, Profound Hypoglycemia and Calcification in Rats
BPC-157 (Body Protection Compound-157) is a synthetic pentadecapeptide derived from a partial sequence of a gastric body protection protein
The activation occurs via trans -phosphorylation of two catalytic tyrosines (Y1234 and Y1235) located in the kinase domain, followed by the subsequent auto-phosphorylation of the two docking tyrosines (Y1349 and Y1356) in the C-terminal tail
However, another mechanism may be that the pentadecapeptide BPC 157 can directly protect against paracetamol induced brain damage
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