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Additives could enhance addictiveness by: Enhancing nicotine content directly Increasing the bioavailability of nicotine so the body reacts more strongly Making it easier to inhale tobacco smoke Producing substances in the smoke which increase addictiveness of nicotine Altering the properties of tobacco smoke, such as the size of the smoke particles

That places CTIHK between two sets of variables: global tobacco industry transformation, international trade relations and supply chain restructuring on one side

If you feel any throbbing or notice bleeding, stop immediately and rest

Therefore, data are presented as median (IQR) or percentage

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