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Both -syn knockout mice and mice administered a short peptide competing at -syn ser129 were able to resist chronic hypoxia-induced cognitive impairment

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References Buse JB, Drucker DJ, Taylor KL, Kim T, Walsh B, Hu H, et al

Pharmacokinetic Summary Half-Life 6.0 days Time for 50% of the drug to be eliminated Steady State ~4.3 weeks Time to reach stable peak/trough levels at each dose Washout Period ~24 days Time until less than 3% of peak level remains Final Peak Level 0.07 mg Peak drug amount at the stopped (washout) dose Model Your Own Schedule Enter your actual doses and timing to see a personalized PK curve with your real data