While motility gains were limited, combining GLP-1s with diet and exercise produced stronger improvements in motility and overall semen health
Because it targets the metabolic process directly rather than suppressing appetite through the central nervous system, it doesnt cause the jittery feeling associated with many weight loss stimulants
Diabetes, Obesity and Metabolism , 24(8), 15531564
Through stimulation of pro-opiomelanocortin (POMC) neurons while simultaneously inhibiting neuropeptide Y/agouti-related peptide neurons in the arcuate nucleus, GLP-1 receptor agonism promotes satiety, reduces meal size, and decreases overall caloric intake [35]
Ania Jastreboff, her co-author and an endocrinologist and associate professor at the Yale School of Medicine