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SPAG5-AS1 inhibited autophagy and aggravated apoptosis of podocytes via SPAG5/AKT/mTOR pathway

In vitro conditions allow cancer cells unrestricted access to nutrients and oxygen, contrasting sharply with the spatial constraints, nutrient gradients, hypoxia, and cell-cell interactions encountered within tumors in vivo 51

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A combination of multi-omics (Bulk RNA sequencing, CUT&Tag detection, and glutathione S-transferase pull-down/mass spectrometry analysis) was employed to investigate underlying mechanisms

(PubMed) Juraschek SP, Guallar E, Appel LJ, Miller ER, 3 rd