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Demand for Novo Nordisks semaglutide drugs and the peptide drugs of its main competitor, Eli Lilly and Company, is tremendous

In official studies, Retatrutide promises a higher efficacy rate, with up to 28.3% weight loss reported, compared to tirzepatide's 20.9%

Hence, the application of nanotechnology could enhance the efficacy and improve their bioavailability by increasing solubility, enhancing plasma half-life, preventing degradation in the intestinal environment, and elevating permeation in the small intestine (Hu et al., 2017)

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Since the introduction of lipid nanoparticle-mRNA formulations, they have emerged as a potent alternative to conventional vaccine platforms