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*Correspondence: Andrey Khlystov, [email protected] This article was submitted to Analytical Chemistry, a section of the journal Frontiers in Chemistry Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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Significant correlations were also observed between changes in plasma nicotine levels from baseline to 65 minutes and cigarettes smoked per day (r = 0.41, P = 0.005), FTCD (r = 0.41, P = 0.004) and CDS (r = 0.36, P = 0.013)