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People with BD taking hepatic enzyme-inducing drugs such as carbamazepine, oxcarbazepine or topiramate have an increased nicotine metabolism, possibly resulting in the urge of heavier smoking and making it more difficulty to quit smoking (68)

DOI: Published online: March 27, 2025 1 Department of Internal Medicine, Gyeongsang National University Changwon Hospital, Gyeongsang National University School of Medicine, Changwon, Korea 2 Department of Radiology, Gyeongsang National University Changwon Hospital, Gyeongsang National University School of Medicine, Changwon, Korea Corresponding Author: Ho Cheol Kim, MD Department of Internal Medicine, Gyeongsang National University Changwon Hospital, Gyeongsang National University School of Medicine, 11 Samjeongja-ro, Seongsan-gu, Changwon 51472, Korea Tel: +82-55-214-3730 Fax: +82-55-214-8618 E-mail: [email protected] 2025 Kosin University College of Medicine

This is a serious problem that sometimes requires surgery to repair, but it does not happen commonly

The BAPC model employs a second-order random walk to smooth the priors for age, period, and cohort effects, enabling the prediction of posterior mortality rates 16

Many of those who died had underlying illnesses and were older