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ROS accumulation is positively correlated with pancreatic fibrosis in both acinar and islet tissues, confirming the role of OxS in fibrosis onset [36]

In the study of glioblastoma, RSL3 inhibits the activity of GPX4, drives the occurrence of ferrozois and induces oxidative death of glioblastoma cells, providing new therapeutic ideas for glioblastoma (Xu et al., 2021)

However, melanocyte precursors, known as melanoblasts, are more difficult to identify since they dont produce melanin and therefore dont usually express those markers, although occasionally DCT and/or KIT are detectable as specific markers 27

I: cognitive and language outcomes