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Those findings were largely ignored - until the emergence of second-generation GLP-1 drugs like semaglutide and tirzepatide

Components included cardiovascular-related death, kidney-related death, persistent 50% estimated glomerular filtration rate (eGFR) reduction, persistent eGFR 15 mL/min/1.73m 2 , and chronic kidney replacement therapy

Articular cartilage restoration procedures are designed to repair and regenerate damaged joint cartilage to preserve long-term knee function and reduce pain

Noguchi M, Fujimoto K, Arai G, Uemura H, Hashine K, Matsumoto H, Fukasawa S, Kohjimoto Y, Nakatsu H et al (2021) A randomized phase III trial of personalized peptide vaccination for castration-resistant prostate cancer progressing after docetaxel