glutathione peroxidase selenium Structure–Activity Correlation between Natural (GPx) and Mimics: A Biomimetic Concept for the Design and Synthesis of More Efficient GPx Mimics - Mugesh - 2001 - Chemistry – A European Journal NADPH oxidase most glutathione peroxides are selenium

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Glutathione plays several neutralize free radicals regenerate vitamins C and E remove mercury from the brain regulate cell growth and death maintain mitochondrial DNA activate antioxidant enzymes Due to its role in preventing cellular damage, many people believe that glutathione can offer numerous health benefits

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The enzyme is located primarily in the peroxisomes but absent in mitochondria of mammalian cells