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The combination of reduced IGFBP binding (increasing local concentration) and enhanced receptor affinity creates a molecule approximately 10 times more potent than native IGF-1 in stimulating tissue growth

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Some people may lose a few pounds during the first month, while others experience more gradual progress as the medication builds in their system

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This was the first trial to demonstrate cardiovascular risk reduction with a GLP-1 receptor agonist in a non-diabetic population