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These autoantibodies against immunomodulatory proteins (including cytokines, chemokines, complement components and cell-surface proteins) could attack tissues of patients, thereby impair host cell signals, perturb immune function, damage organ systems, and increase COVID-19 severity 36

One pathway (GLP-1) handles the incretin response, while the other pathway (amylin) handles the satiety response

Proc Natl Acad Sci U S A9436213626

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Researchers want to understand how weight loss might affect cancer growth, hormones, metabolism and the immune system, for people who have a high risk of cancer recurrence