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While oral supplements are useful for maintenance, IV therapy provides faster and more powerful results due to higher bioavailability
Data source, study protocol and patient selection Data for this investigation were accessed through the TriNetX Analytics platform, a global collaborative health research network widely used in numerous prominent epidemiological studies (Supplementary appendix) 43,44,45
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Common Clinical Use The most commonly used PDE-4 inhibitor is roflumilast, indicated for: Severe COPD associated with chronic bronchitis Patients with frequent COPD exacerbations It is usually used as add-on therapy to bronchodilators
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