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Recent studies have revealed that cancer cells with KRAS mutations utilize amino acids such as glutamine and leucine to accelerate energy metabolism and redox balance through GSH synthesis and macromolecule biosynthesis

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However, following intestinal I/R injury, the injured intestinal epithelium becomes leaky, letting bacterial components such as LPS to reach the systemic circulation (Wang et al., 2019

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Despite the concern for increased blood pressure with phentermine monotherapy, improved blood pressure control was observed after phentermine/topiramate ER treatments

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