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Instead, any shifts in lab values are usually indirect: TSH (Thyroid Stimulating Hormone): In large-scale datasets like the Epic Cosmos study, researchers observed that some patients see a slight decrease in TSH levels

doi: 10.1001/jamainternmed.2022.0338

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Since they are not FDA-approved, they do not have standardized FDA-required labeling, including side-effect warnings, boxed warnings, or risk evaluation and mitigation strategies that apply to approved drugs