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Mutations in the SLC52A2 and SLC52A3 have been reported to cause Brown-Vialetto-Van Laere (BVVL) and Fazio-Londe (FL) [22,23]
The concentrations used, the cell types tested, and the exposure conditions do not directly translate to what happens when a human applies a cream or injects a solution
doi: 10.1038/cdd.2015.158 15
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Feedback inhibition by thiols outranks glutathione depletion: a luciferase-based screen reveals glutathione-deficient -ECS and glutathione synthetase mutants impaired in cadmium-induced sulfate assimilation
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