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About this article Cite this article Gu, Ym., Yuan, Qn., Li, X

J Hirnforsch 38:323330 Zhang J, Hu J, Ding J-H, Yao H-H, Hu G (2005) 6-Hydroxydopamine-induced glutathione alteration occurs via glutathione enzyme system in primary cultured astrocytes

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GPX4 deficiency enhanced cellular LPO and specifically attenuated the STING DNA-sensing pathway, thereby inhibiting innate antiviral immune responses against HSV-1 and promoting HSV-1 replication in vivo (Jia et al., 2020) These suggested that GPX4 facilitated STING activation by maintaining redox homeostasis of lipids (Jia et al., 2020)

For DSIP alone, we spent several days exploring the literature to pinpoint the peptides most conclusive therapeutic uses and the studies supporting its use toward those ends