Massage, stretching, water immersion, cold exposure, and active recovery are all examples of compressive techniques
Moreover, microbial transplantation studies in germ-free mice with human commensals containing a functional (but not a deletion mutant) microbial cutC gene (responsible for cholineTMA transformation) (23) and genetic manipulation (both gain of function and loss of function) of host hepatic flavin monooxygenase 3 have been shown to modulate host TMAO levels, platelet responsiveness, and thrombosis potential in vivo (24)
That's why most research protocols build in a break between cycles, often called a washout period, to let the body reset before starting again
Released as a repair signal when collagen is damaged
The clinical evidence is clear, the mechanism is understood, and patients report real symptom relief