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Pu S-Y, Huang Y-L, Pu C-M, Kang Y-N, Hoang KD, Chen K-H, et al

When utilizing MRgFUS and electrical fields for BBB opening, since the BTB is more permeable in some areas, it might be best to target the areas of the BBB and BTB that display low permeability

The FDA cited concerns including potential heart-related adverse events in available safety data and the general Category 2 rationale of insufficient safety information for compounding

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