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Additionally, ventricular diastolic sarcoplasmic reticulum calcium leakage has been closely linked to ventricular systolic dysfunction and arrhythmias
Researchers first identified it decades ago and later discovered that levels tend to decline with age
Indeed, at the end of the observation, roughly 2 out of 3 patients were receiving the 7 mg maintenance dose and only 1 out of 4 had escalated to the maximum licenced 14 mg dose
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Tirzepatide, a dual GLP-1/GIP receptor agonist has been approved for glycaemic control in type 2 diabetes as well as for obesity management leading in up to 22.5% WL in phase 3 obesity trials
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