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Initiation of GLP-1RA was defined as a new prescription of any GLP-1RA available in Italy (exenatide BID, exenatide OW, lixisenatide, liraglutide, dulaglutide, semaglutide OW, oral semaglutide) for patients who had never been treated with the same compound before, as evident from the diabetes treatment history recorded in the electronic chart

However, in actual clinical practice, the use of insulin is often delayed until A1C approaches 9%, and many people with type 2 diabetes have already developed diabetes-related complications by the time they begin treatment with insulin