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The small hydrophilic molecules include glucuronic acid, glutathione, sulfate, amino acids, and a methyl group, which are catalyzed by glucuronyl transferases, glutathione transferases, sulfotransferases, amino acid transferases, and N- and O-methyltransferases, respectively [21]

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Fatty acyl-CoA undergoes -oxidation within mitochondria to produce energy, and L-carnitine is transported to the cytoplasm again by CACT (As show in Figure 1)