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Use a protein-first, fiber-smart, hydration-supported, smaller-meal pattern and adjust based on symptoms

Resting Energy Expenditure Small-scale indirect calorimetry studies suggest tirzepatide modestly increases resting energy expenditure (REE) beyond what weight loss alone predicts, an effect not consistently seen with liraglutide or semaglutide at approved doses

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For example, introduction of injectable and oral long-acting formulations has revolutionized the way these drugs are administered

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