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For instance, administration of UroA to Caenorhabditis elegans led to a significant extension of lifespan, while rodent studies showed enhanced muscle endurance and reduced signs of muscle ageing (Reference Ryu, Mouchiroud and Andreux15)

These changes in membrane proteins and lipids contribute to functional and structural alterations that decrease erythrocyte membrane stability and deformability and trigger premature RBC removal [12, 24]

Glutathione, in its role as an antioxidant, supports healthy mitochondrial function

Poudel, K

These include the inhibition of sarcoplasmic reticulum Ca2+ATPase, depletion of intracellular calcium, and blocking of calciumdependent potassium channels and voltagedependent calcium channels