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The UK Summary of Product Characteristics (SmPC) for semaglutide, liraglutide and tirzepatide specifically states they should not be used during breast-feeding due to lack of human data

Before use, it must be reconstituted by mixing it with a sterile liquid, such as bacteriostatic water

Moutal, A

Heres what we know from the available data thus far: No reported toxicity in preclinical injection studies No behavioral or pathological abnormalities observed No adverse safety signals in topical skin care studies Theoretical concerns about copper overload exist, but no study to date has demonstrated this outcome with GHK-Cu