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Robertson DG, Datta K, Wells D, Egnash L, Robosky L, Manning M, et al
J Econ Entomol 108:14861494
In brief, SUSTAIN 6 was a randomized, double-blind, placebo-controlled, parallel-group trial to evaluate once-weekly semaglutide 0.5 or 1.0 mg vs volume-matched placebo over a 104-week treatment period plus a 5-week follow-up period
Preservation of lean muscle mass: While weight loss interventions often result in the loss of lean muscle mass, Semaglutides effects on appetite regulation and protein metabolism may help preserve muscle mass during periods of caloric restriction or weight loss, promoting a leaner and more defined physique