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Instruct patients to immediately inform their healthcare provider if pregnant or planning to become pregnant [see Use in Specific Populations (8.1)]

Tirzepatide, on the other hand, is a dual-functioning agonist for both the glucose-dependent insulinotropic polypeptide (GIP) and GLP-1 receptors, thereby engaging with both receptor types

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The approved dosing regimen begins at 0.25 mg once weekly for four weeks (an initiation dose to improve tolerability), then increases to 0.5 mg once weekly, with further increases to 1 mg or 2 mg if needed for glycaemic control

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