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The primary hypothesis was that IcoSema is superior to semaglutide 1.0 mg treatment in terms of change in HbA 1c from baseline to week 52

The standard schedule exists specifically to minimize side effects

52 , 53 , 54 , 55 As such, weight loss of 10%15% is recommended in people with complications of overweight and obesity, such as gastroesophageal reflux disease, osteoarthritis, obstructive sleep apnoea, nonalcoholic steatohepatitis and diabetes

Muscle pain is not a direct side effect of using Ozempic but that doesnt mean the drug isnt entirely to blame

Newer therapy with potentially greater weight loss in clinical trials