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Cogn Psychol

A Phase 3 Randomized, Double-Blind, Placebo-Controlled Trial of Ganitumab or Placebo in Combination with Gemcitabine as First-Line Therapy for Metastatic Adenocarcinoma of the Pancreas: the GAMMA Trial

Seizures initiate the apoptotic pathway through depleting energy and the accumulation of Ca + 2 inside the mitochondria, activating both extrinsic (expression of death receptors on the cell surface) and intrinsic factors (mitochondrial dysfunction) that in turn induce BAX release

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