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Dosing matters because GHK-CU operates through gene expression modulation

They are not intended to diagnose, treat, cure, or prevent any disease, and are not approved for human or animal administration

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The practice comes from observations that continuous peptide use may reduce effectiveness over time and that breaks allow receptor sensitivity to reset

Interestingly, there is a coincidence between MET peak expression and the early and late stages of neurodevelopmental processes such as dendritic morphology, neurite outgrowth, and synaptogenesis (Gutierrez et al., 2004