doi: 10.1210/clinem/dgac013 [DOI] [PubMed] [Google Scholar] 29.Fahrenfort JJ, Wilterdink AML, Van der Veen E
Platelets, when activated, form aggregates with erythrocytes, monocytes, and neutrophils both in patients and in murine models (Wun et al., 1997
The STEP UP trial, a Phase 3b study published in The Lancet Diabetes & Endocrinology in 2025, evaluated a 7.2 mg weekly injection dose in over 1,400 adults with obesity (BMI of 30 or higher) and without diabetes
Alexander said the FDAs current evaluation of these potential side effects is the correct avenue to aggregate, report, and further investigate medication-related side effects to understand if there are additional minor to serious side effects that may not have been seen or identified as significant during clinical trials
We encourage women to talk about this with their clinician as there are evidence-based approaches that can help them navigate these issues