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Copper overloads are characterized by a t 1/2 of 9-10 h for the decrease in GSH and of 4 h for decreases in the GSH/GSSG ratio, the latter being the most sensitive indicator of copper excess [11]

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As a result, the addition of inhibitor remarkably compromised the cytotoxicity of NSBSO (Fig

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This pro-inflammatory state can lead to the creation of antibodies, which may eventually launch an attack against the thyroid