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Similarly, genetic variants affecting metabolic rate (FTO rs9939609) and appetite regulation (MC4R rs17782313) can support a more informed conversation with your provider about realistic timelines for weight change and side effect management when combined with sertraline

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So I will go first with that one

Notably, this regulation was not one-way

One of the most commonly cited trials (Arjinpathana & Asawanonda, 2012) used 500mg per day over 4 weeks and reported a significant reduction in melanin index versus placebo