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Performance-enhancing drugs (PEDs) marketed as "research compounds" include unregulated peptides intended to modulate the growth hormone-insulin-like growth factor-1 (GH-IGF-1) axis

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Despite the short half-life of the endogenous GLP-1, the interplay of peripheral and central GLP-1 receptor signalling helps achieve glycaemic control and energy intake by slowing gastric emptying and reducing caloric intake (Figure 2) [2,20]

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