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Rare mutations in SLC22A5 can cause hypoglycemia and liver problems from infancy, and this is one of the genetic conditions that is usually screened for at birth

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Src phosphorylation of micro-receptor is responsible for the receptor switching from an inhibitory to a stimulatory signal

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the broad, gradual nature of the loss over a wide temperature range suggests decomposition/char formation of the confined organic species and strong hostguest interactions or confinement effects that spread the decomposition process to high temperature