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[] HSP-70 deactivates JNK and prevents the activation of B-cell lymphoma-2 (BCL-2)associated agonist of cell death (BAD) and BCL-2associated X protein (BAX) in intrinsic apoptosis signaling, [] and it is a therapeutic target in AKI

Slower gastric emptying Slows the rate at which the stomach empties, extending the physical sensation of fullness and flattening post-meal blood-sugar curves

Any unexplained or persistent change in stool colour warrants prompt medical assessment to exclude serious underlying pathology

doi: 10.1371/journal.ppat.1010913 79 Martn-SierraCMartinsRCouceloMAbrantesAMCaetano OliveiraRTralhoJGet al

Common Side Effects Semaglutides most commonly reported side effects involve the gastrointestinal system